| LC control no. | sh 00001691 |
|---|---|
| LC classification | RM666.S714 |
| Topical heading | Statins (Cardiovascular agents) |
| Variant(s) | Hydroxymethylglutaryl coenzyme A reductases--Inhibitors Statin drugs |
| See also | Anticholesteremic agents Enzyme inhibitors |
| Found in | Work cat.: Ebrahim, S. What role for statins?, 1999: p. iii (Statins are a new class of drugs that lower blood cholesterol) Heart Information Network WWW Site, 12 Jan. 2000: Statins page (The most popular class of medications for cholesterol are known as "Statins") Medline search, 13 Jan. 2000 (titles: 452 hits; term used as proposed) Hurst's the heart, 1998: p. 1572 (Four classes of lipid-lowering drugs are currently available in the U.S. for treatment of hyperlipidemia: HMG-CoA reductase inhibitors (statins); bile-acid sequestrants (resins); nicotinic acid (niacin); and fibric-acid derivative (fibrates). Statins achieve the greatest LDL lowering of available hypolipemic drugs. Currently available statins are fluvastatin (Lescol); lovastatin (Mevacor); pravastatin (Pravachol); simvastatin (Zocor); and atorvastatin (Lipitor). The primary action of these drugs is to inhibit HMG-CoA reductase, the rate-limiting enzyme in the biosynthesis of cholesterol) MESH (Hydroxymethylglutaryl-CoA Reductase Inhibitors) Washington Post Health section, June 26, 2001: p. 12 (statin drugs) |
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