| LC control no. | sh2017000049 |
|---|---|
| LC classification | QH603.G55 |
| Topical heading | Glycocalyces |
| Variant(s) | Cell coats Coats, Cell Coats, Pericellular Glycocalices Glycocalix Glycocalyx Matrices, Pericellular PCMs (Pericellular matrices) Pericellular coats Pericellular matrices |
| See also | Extracellular polymeric substances Cell membranes |
| Found in | Work cat: Brown, M.L. Examination of mechanisms of enhanced resistance to iodine in biofilms of Pseudomonas aeruginosa, [1994]: abstr. (Biofilms are complex conglomerations of microbial cells, organic molecules, and inorganic molecules enmneshed in a glycocalyx matrix. ... This study demonstrates that povidone-iodine resistance in a biofilm of P. aeruginosa is due to the protective layering of cells within the interconnected glycocalyx which increases the time required to detach cells and, therefore, the time required for iodine to contact cells in the deepest layers of the biofilm) MeSH browser, Dec. 22, 2016 (Glycocalyx ... The carbohydrate-rich zone on the cell surface. This zone can be visualized by a variety of stains as well as by its affinity for lectins. Although most of the carbohydrate is attached to intrinsic plasma membrane molecules, the glycocalyx usually also contains both glycoproteins and proteoglycans that have been secreted into the extracellular space and then adsorbed onto the cell surface) UFs (cell coat; glycocalix) MeSH tree structures (directly under: Cell membrane structures) Trends in parasitology, May 2011: p. 204 (Glycocalyx (plural glycocalyces): the layer of carbohydrate that surrounds animal cells. It is formed by many individual carbohydrate chains (glycans), covalently attached to extracellular-facing plasma membrane proteins/protein domains and lipids) Biophysical journal, Mar. 2013: p. 961 (Between the outermost edge of the cell membrane and that part of the extracellular matrix nearest to the cell lies a part of the cell that is largely overlooked: the pericellular matrix (PCM) or glycocalyx. The PCM was initially detected in electron microscopy studies of polysaccharide distribution as a fuzzy coat that covered, for example, the surface of cells lining the capillary lumen, or the tips of microvilli in intestinal epithelia. This glycocalyx could extend several microns from the cell surface. ... The PCM is composed primarily of hyaluronic acid (HA), a flexible highly anionic linear polymer of disaccharide repeats that also forms the gel within the vitreous body of the eyeball. Existing in detachment from the cell, it is a major constituent of many extracellular matrices. HA chains are produced by HA synthases on the cell membrane which project the long molecules into the extracellular space) International journal of cell biology, 2015: v. 2015, Article ID 701738, p. 1 (In this targeted review, we summarize evidence suggesting that defective wound healing in diabetics is causally linked, at least in part, to hyperglycemia-induced changes in the status of hyaluronan (HA) that resides in the pericellular coat (glycocalyx) of endothelial cells of small cutaneous blood vessels) Thiriet, M. Cell and tissue organization in the circulatory and ventilatory systems, ©2011: pp. 127-128 (Glycocalyx is a highly charged layer of extracellular polymeric material attached to the plasma membrane of epithelial and other cells. ... This layer functions as a barrier between the cell and its surrounding that must be crossed by nutrients, messengers, and drugs. It cushions the plasma membrane from stresses. Cells have distinct glycocalices that permit their identification) |
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