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Statins (Cardiovascular agents)

LC control 00001691
LC classificationRM666.S714
Topical headingStatins (Cardiovascular agents)
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Variant(s)Hydroxymethylglutaryl coenzyme A reductases--Inhibitors
Statin drugs
See alsoAnticholesteremic agents
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Enzyme inhibitors
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Found inWork cat.: Ebrahim, S. What role for statins?, 1999: p. iii (Statins are a new class of drugs that lower blood cholesterol)
Heart Information Network WWW Site, 12 Jan. 2000: Statins page (The most popular class of medications for cholesterol are known as "Statins")
Medline search, 13 Jan. 2000 (titles: 452 hits; term used as proposed)
Hurst's the heart, 1998: p. 1572 (Four classes of lipid-lowering drugs are currently available in the U.S. for treatment of hyperlipidemia: HMG-CoA reductase inhibitors (statins); bile-acid sequestrants (resins); nicotinic acid (niacin); and fibric-acid derivative (fibrates). Statins achieve the greatest LDL lowering of available hypolipemic drugs. Currently available statins are fluvastatin (Lescol); lovastatin (Mevacor); pravastatin (Pravachol); simvastatin (Zocor); and atorvastatin (Lipitor). The primary action of these drugs is to inhibit HMG-CoA reductase, the rate-limiting enzyme in the biosynthesis of cholesterol)
MESH (Hydroxymethylglutaryl-CoA Reductase Inhibitors)
Washington Post Health section, June 26, 2001: p. 12 (statin drugs)